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Account run by the team @bonfire@indieweb.social who is facilitating the design and development of the Open Science Network. More about the project: https://openscience.network/about
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ivan
ivan  ·  last week
Journal of clinical lipidology
Saturated fats and cardiovascular health: Current evidence and controversies
Kevin C. Maki, Mary R. Dicklin, Carol F. Kirkpatrick
journalArticle
doi:10.1016/j.jacl.2021.09.049
A diet high in saturated fatty acids (SFA) is a suspected contributor to atherosclerotic cardiovascular disease (ASCVD) risk, in large part because of an effect to raise the low-density lipoprotein cholesterol (LDL-C) concentration. Most dietary guidance from health authorities advocates limiting intake of SFA, particularly for people with clinical ASCVD, dyslipidemia, or diabetes mellitus. However, recent reviews have highlighted controversies regarding SFA intake and cardiovascular health. This brief editorial commentary includes a discussion of the evidence regarding SFA intake and cardiovascular health, outlines gaps in the available evidence, and proposes tentative conclusions based on what is known today about SFA consumption and ASCVD risk. Results from observational studies demonstrate that dietary patterns with lower average intakes of SFA are associated with favorable cardiovascular outcomes. Additionally, although the number of randomized controlled trials testing the effects of reducing SFA intake on ASCVD outcomes is limited, the available evidence supports the view that replacing SFA with unsaturated fatty acids, particularly polyunsaturated fatty acids, may reduce ASCVD risk. Beyond raising LDL-C and atherogenic lipoprotein particle concentrations, higher intakes of SFA may influence pathways affecting inflammation, cardiac rhythm, hemostasis, apolipoprotein CIII production, and high-density lipoprotein function. However, the impacts of these effects on ASCVD risk remain uncertain. In the authors' view, the totality of the evidence supports the current recommendation to limit SFA intake to
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Mayel
Mayel  ·  3 weeks ago
Zenodo
REFLOW Architecture and Manual for Distributed Network Setup and Maintenance
Mayel de Borniol
report
July 9, 2021
This deliverable provides an introduction and a manual to the REFLOW OS, a system designed to operate federated nodes constituting the REFLOW network backend infrastructure. It is targeted for adoption by the Free and Open Source communities at large
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Mayel boosted
Open Science Network
Open Science Network  ·  2 months ago

The http://openscience.network project is more than a #federated digital space. It's a network to collectively discover, produce and participate to the most relevant #openscience discussions on the fediverse and beyond.

In the public homepage, the editorial team pins posts for anyone to read - as an alternative to the most recent activities (often meaningless to the general audience )

Imagine every university, collective and lab owning their federated digital space and radically transforming their usual social networking presence in powerful ways:

- Curate and organize discussions in topics, moving beyond feeds and toward structured journals composed of federated discussions and links

- Discover and read papers directly from the scientist social profile


- Collaborate on new ideas in the open, instead of being siloed inside centralized platforms, publish papers from the fediverse

And this is only the beginning! Support us building the next infrastructure for open science!