Björn Brembs @brembs · activity timestamp 4 years ago Sensitivity to expression levels underlies differential dominance of a putative null allele of the Drosophila tβh gene in behavioral phenotypes Differential dominance occurs when genes associated with several phenotypes (pleiotropic genes) show different modes of inheritance (e.g., recessive, dominant or overdominant) depending on the phenotype. This study reveals that differential sensitivity to gene expression levels can mediate differential dominance, which can be a significant challenge for standard transgenic techniques commonly used to elucidate gene function. Reply Boost Like More actions Copy link Flag this media Block
